Septra (Sulfamethoxazole/Trimethoprim) Information

The active ingredients in Septra are:

• Sulfamethoxazole: 400 mg
• Trimethoprim: 80 mg

Other inactive ingredients may include:

• Lactose
• Magnesium stearate
• Microcrystalline cellulose
• Hydroxypropylmethylcellulose

Common side effects include:

• Nausea
• Vomiting
• Diarrhea
• Loss of appetite
• Rash

Serious side effects requiring immediate medical attention:

• Severe allergic reactions (rash, swelling, difficulty breathing)
• Severe skin reactions (blistering, peeling)
• Jaundice or signs of liver problems
• Unusual tiredness, weakness, or fever
• Signs of a blood disorder (easy bruising, unusual bleeding, sore throat)

Septra is typically taken orally, either as a tablet or liquid, once or twice daily depending on the severity of the infection. It is usually taken with food to reduce stomach upset.

Important considerations:

• Take the medication exactly as prescribed by your doctor.
• Complete the full course of antibiotics, even if you feel better before the medication is finished.
• If you miss a dose, take it as soon as possible, but skip the missed dose if it's almost time for your next dose.

Septra may interact with other medications, so inform your healthcare provider of all the medications you are currently taking.

Common interactions include:

• Warfarin: Septra may increase the risk of bleeding.
• Methotrexate: Septra can increase the side effects of methotrexate.
• Diuretics (e.g., furosemide): May increase the risk of kidney problems.

Septra usually begins to work within 24 to 48 hours of taking the medication. Symptoms may improve quickly, but it is important to finish the entire prescribed course of treatment to ensure the infection is fully treated.

If you experience any serious side effects such as severe allergic reactions, skin reactions, or signs of liver problems, stop taking Septra and seek immediate medical attention.

It is important to report any unusual or severe symptoms to your healthcare provider as soon as possible.